Difference between revisions of "RodA"
| Line 34: | Line 34: | ||
{{SubtiWiki category|[[cell shape]]}}, | {{SubtiWiki category|[[cell shape]]}}, | ||
{{SubtiWiki category|[[cell envelope stress proteins (controlled by SigM, W, X, Y)]]}}, | {{SubtiWiki category|[[cell envelope stress proteins (controlled by SigM, W, X, Y)]]}}, | ||
| − | {{SubtiWiki category|[[essential genes]]}} | + | {{SubtiWiki category|[[essential genes]]}}, |
| + | {{SubtiWiki category|[[membrane proteins]]}} | ||
= This gene is a member of the following [[regulons]] = | = This gene is a member of the following [[regulons]] = | ||
| Line 82: | Line 83: | ||
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
| − | * '''Interactions:''' | + | * '''[[SubtInteract|Interactions]]:''' |
| + | ** part of the [[cell wall biosynthetic complex]] {{PubMed|21636744,21636745}} | ||
| − | * '''Localization:''' | + | * '''Localization:''' |
| + | ** integral membrane protein {{PubMed|21636744}} | ||
| + | ** forms circumferentially moving patches {{PubMed|21636744}} | ||
=== Database entries === | === Database entries === | ||
Revision as of 05:18, 11 July 2011
- Description: control of cell shape and elongation
| Gene name | rodA |
| Synonyms | ywcF, ipa-42d |
| Essential | yes PubMed |
| Product | SEDS protein |
| Function | control of cell shape and elongation |
| MW, pI | 43 kDa, 8.759 |
| Gene length, protein length | 1179 bp, 393 aa |
| Immediate neighbours | nfrA, ywcE |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
cell shape, cell envelope stress proteins (controlled by SigM, W, X, Y), essential genes, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU38120
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: ftsW/rodA/spoVE family (according to Swiss-Prot) SEDS proteins (shape, elongation, division, and sporulation)
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- part of the cell wall biosynthetic complex PubMed
Database entries
- Structure:
- UniProt: P39604
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: rodA PubMed
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
- Charles Moran, Emory University, NC, USA homepage
Your additional remarks
References
Gonçalo Real, Allison Fay, Avigdor Eldar, Sérgio M Pinto, Adriano O Henriques, Jonathan Dworkin
Determinants for the subcellular localization and function of a nonessential SEDS protein.
J Bacteriol: 2008, 190(1);363-76
[PubMed:17981970]
[WorldCat.org]
[DOI]
(I p)
A O Henriques, P Glaser, P J Piggot, C P Moran
Control of cell shape and elongation by the rodA gene in Bacillus subtilis.
Mol Microbiol: 1998, 28(2);235-47
[PubMed:9622350]
[WorldCat.org]
[DOI]
(P p)
