Difference between revisions of "ComP"
| Line 12: | Line 12: | ||
|style="background:#ABCDEF;" align="center"| '''Product''' || [[two-component systems|two-component]] sensor kinase | |style="background:#ABCDEF;" align="center"| '''Product''' || [[two-component systems|two-component]] sensor kinase | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Function''' || regulation of genetic competence and quorum sensing | + | |style="background:#ABCDEF;" align="center"|'''Function''' || regulation of [[genetic competence]] and [[quorum sensing]] |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 89 kDa, 7.997 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 89 kDa, 7.997 | ||
| Line 87: | Line 87: | ||
* '''Interactions:''' [[ComP]]-[[ComA]] | * '''Interactions:''' [[ComP]]-[[ComA]] | ||
| − | * '''Localization:''' cell membrane | + | * '''Localization:''' cell membrane {{PubMed|18763711}} |
| + | |||
=== Database entries === | === Database entries === | ||
| Line 135: | Line 136: | ||
<pubmed>12576575 </pubmed> | <pubmed>12576575 </pubmed> | ||
==Original Publications== | ==Original Publications== | ||
| − | <pubmed>11133937,8643670,12067344,10094672,10419951,2116363,9274030 </pubmed> | + | <pubmed>11133937,8643670,12067344,10094672,10419951,2116363,9274030 18763711 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 13:58, 27 December 2010
- Description: two-component sensor kinase, detects extracellular ComX
| Gene name | comP |
| Synonyms | |
| Essential | no |
| Product | two-component sensor kinase |
| Function | regulation of genetic competence and quorum sensing |
| MW, pI | 89 kDa, 7.997 |
| Gene length, protein length | 2307 bp, 769 aa |
| Immediate neighbours | comA, comX |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
genetic competence, protein modification, transcription factors and their control, quorum sensing, membrane proteins, phosphoproteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU31690
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: autophosphorylation, phosphorylation of ComA
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains: eight transmembrane segments
- Modification: autophosphorylation on a His residue
- Cofactor(s):
- Effectors of protein activity: ComX (extracellular)
- Localization: cell membrane PubMed
Database entries
- Structure:
- UniProt: Q99027
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: comP PubMed
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Leendert W Hamoen, Gerard Venema, Oscar P Kuipers
Controlling competence in Bacillus subtilis: shared use of regulators.
Microbiology (Reading): 2003, 149(Pt 1);9-17
[PubMed:12576575]
[WorldCat.org]
[DOI]
(P p)
Original Publications
