Difference between revisions of "YvrHa"
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| + | = [[Categories]] containing this gene/protein = | ||
| + | {{SubtiWiki category|[[transcription]]}}, | ||
| + | {{SubtiWiki category|[[sigma factors and their control]]}}, | ||
| + | {{SubtiWiki category|[[acid stress proteins (controlled by YvrI-YvrHa)]]}} | ||
| + | |||
| + | = This gene is a member of the following [[regulons]] = | ||
| + | {{SubtiWiki regulon|[[YvrHb regulon]]}}, | ||
| + | {{SubtiWiki regulon|[[YvrI-YvrHa regulon]]}} | ||
=The gene= | =The gene= | ||
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=The protein= | =The protein= | ||
Revision as of 23:17, 8 December 2010
- Description: co-sigma factor (with YvrI)
| Gene name | yvrHa |
| Synonyms | rsoA |
| Essential | no |
| Product | co-sigma factor (with YvrI) |
| Function | RNA polymerase sigma factor |
| MW, pI | 9.5 kDa, 4.69 |
| Gene length, protein length | 240 bp, 79 amino acids |
| Immediate neighbours | yvrHb, yvrI |
| Gene sequence (+200bp) | Protein sequence |
Genetic context 
| |
Contents
Categories containing this gene/protein
transcription, sigma factors and their control, acid stress proteins (controlled by YvrI-YvrHa)
This gene is a member of the following regulons
YvrHb regulon, YvrI-YvrHa regulon
The gene
Basic information
- Locus tag:
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: does not exist
Additional information
The sequence of the former yvrH gene was corrected, and does now contain two genes, yvrHa and yvrHb.
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains: corresponds to region 2 of a sigma factor PubMed
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
Database entries
- Structure:
- UniProt: C0H3R4
- KEGG entry: no entry
- E.C. number:
Additional information
Expression and regulation
- Regulation: induced by acidic growth conditions PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
John Helmann, Cornell University, USA Homepage
Your additional remarks
References
Shawn R MacLellan, Veronica Guariglia-Oropeza, Ahmed Gaballa, John D Helmann
A two-subunit bacterial sigma-factor activates transcription in Bacillus subtilis.
Proc Natl Acad Sci U S A: 2009, 106(50);21323-8
[PubMed:19940246]
[WorldCat.org]
[DOI]
(I p)
Shawn R MacLellan, John D Helmann, Haike Antelmann
The YvrI alternative sigma factor is essential for acid stress induction of oxalate decarboxylase in Bacillus subtilis.
J Bacteriol: 2009, 191(3);931-9
[PubMed:19047353]
[WorldCat.org]
[DOI]
(I p)
Shawn R MacLellan, Tina Wecke, John D Helmann
A previously unidentified sigma factor and two accessory proteins regulate oxalate decarboxylase expression in Bacillus subtilis.
Mol Microbiol: 2008, 69(4);954-67
[PubMed:18573182]
[WorldCat.org]
[DOI]
(I p)
