Difference between revisions of "PhoR"

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= [[Categories]] containing this gene/protein =
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{{SubtiWiki category|[[phosphate metabolism]]}},
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{{SubtiWiki category|[[protein modification]]}},
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{{SubtiWiki category|[[transcription factors and their control]]}},
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{{SubtiWiki category|[[regulators of core metabolism]]}},
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{{SubtiWiki category|[[sporulation proteins]]}},
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{{SubtiWiki category|[[general stress proteins (controlled by SigB)]]}},
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{{SubtiWiki category|[[membrane proteins]]}},
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{{SubtiWiki category|[[phosphoproteins]]}}
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= This gene is a member of the following [[regulons]] =
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{{SubtiWiki regulon|[[CcpA regulon]]}},
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{{SubtiWiki regulon|[[PhoP regulon]]}},
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{{SubtiWiki regulon|[[SigB regulon]]}},
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{{SubtiWiki regulon|[[SigE regulon]]}}
  
 
=The gene=
 
=The gene=
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= Categories containing this gene/protein =
+
 
{{SubtiWiki category|[[phosphate metabolism]]}},
 
{{SubtiWiki category|[[protein modification]]}},
 
{{SubtiWiki category|[[transcription factors and their control]]}},
 
{{SubtiWiki category|[[regulators of core metabolism]]}},
 
{{SubtiWiki category|[[sporulation proteins]]}},
 
{{SubtiWiki category|[[general stress proteins (controlled by SigB)]]}},
 
{{SubtiWiki category|[[membrane proteins]]}},
 
{{SubtiWiki category|[[phosphoproteins]]}}
 
 
=The protein=
 
=The protein=
  

Revision as of 22:19, 8 December 2010

  • Description: two-component sensor kinase, regulation of phosphate metabolism

Gene name phoR
Synonyms
Essential no
Product two-component sensor kinase
Function regulation of phosphate metabolism
MW, pI 64 kDa, 5.957
Gene length, protein length 1737 bp, 579 aa
Immediate neighbours polA, phoP
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
PhoR context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

phosphate metabolism, protein modification, transcription factors and their control, regulators of core metabolism, sporulation proteins, general stress proteins (controlled by SigB), membrane proteins, phosphoproteins

This gene is a member of the following regulons

CcpA regulon, PhoP regulon, SigB regulon, SigE regulon

The gene

Basic information

  • Locus tag: BSU29100

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: autophosphorylation, phosphorylation of PhoP
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains: two transmembrane segments, C-terminal histidine phosphotransferase domain
  • Modification: autophosphorylation on a His residue
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:

Database entries

  • Structure: 3CWF (extracellular PAS domain) PubMed
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • carbon catabolite repression (CcpA) PubMed
    • expressed under conditions of phosphate limitation (PhoP) PubMed
    • expressed in post-exponential phase (ScoC) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Marion Hulett, University of Illinois at Chicago, USA Homepage

Your additional remarks

References