YqfL

• Description: Modulator of CcpN activity
  
  

Gene name	yqfL
Synonyms
Essential	no
Product	modulator of CcpN activity
Function	inhibits CcpN activity
MW, pI	30,4 kDa, 5.78
Gene length, protein length	810 bp, 270 amino acids
Immediate neighbours	yqxD, ccpN
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU25240

Database entries

• DBTBS entry: [1]

• SubtiList entry:[2]

Categories containing this gene/protein

carbon core metabolism, transcription factors and their control

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: negative effector of CcpN activity PubMed

• Protein family: pyruvate, phosphate dikinase regulatory protein family (according to Swiss-Prot) pyruvate, phosphate dikinase regulatory protein family

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains: nucleotide binding domain (ATP) (151–158)

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P54470

• KEGG entry: [3]

• E.C. number: 2.7.-.-

Expression and regulation

• Operon: ccpN-yqfL PubMed

• Sigma factor:

• Regulation: constitutive PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• Antibody:

Labs working on this gene/protein

Stephane Aymerich, Microbiology and Molecular Genetics, INRA Paris-Grignon, France

References

Pascale Servant, Dominique Le Coq, Stéphane Aymerich
CcpN (YqzB), a novel regulator for CcpA-independent catabolite repression of Bacillus subtilis gluconeogenic genes.
Mol Microbiol: 2005, 55(5);1435-51
[PubMed:15720552] [WorldCat.org] [DOI] (P p)