YfiZ

• Description: ABC transporter for the siderophore schizokinen and arthrobactin (permease), works with ATPase YusV
  
  

Gene name	yfiZ
Synonyms
Essential	no
Product	ABC transporter for the siderophore schizokinen and arthrobactin (permease)
Function	iron acquisition
MW, pI	34 kDa, 9.62
Gene length, protein length	999 bp, 333 aa
Immediate neighbours	yfiY, yfhA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU08450

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

Categories containing this gene/protein

ABC transporters, acquisition of iron, iron metabolism, membrane proteins

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: FecCD subfamily (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: YusV-(YfhA-YfiZ)-YfiY PubMed

• Localization: cell membrane PubMed

Database entries

• Structure:

• UniProt: O31568

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:
  • repressed unless the cells enter an iron starvation (Fur) PubMed

• Regulatory mechanism:
  • Fur: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Juliane Ollinger, Kyung-Bok Song, Haike Antelmann, Michael Hecker, John D Helmann
Role of the Fur regulon in iron transport in Bacillus subtilis.
J Bacteriol: 2006, 188(10);3664-73
[PubMed:16672620] [WorldCat.org] [DOI] (P p)

Noel Baichoo, Tao Wang, Rick Ye, John D Helmann
Global analysis of the Bacillus subtilis Fur regulon and the iron starvation stimulon.
Mol Microbiol: 2002, 45(6);1613-29
[PubMed:12354229] [WorldCat.org] [DOI] (P p)

Y Quentin, G Fichant, F Denizot
Inventory, assembly and analysis of Bacillus subtilis ABC transport systems.
J Mol Biol: 1999, 287(3);467-84
[PubMed:10092453] [WorldCat.org] [DOI] (P p)