EcsA

• Description: ABC transporter (ATP-binding protein), mutation affects proteolysis by RasP (no processing of RsiW and FtsL)
  
  

Gene name	ecsA
Synonyms	prsT, ecs-26, yhaD
Essential	no
Product	ABC transporter (ATP-binding protein)
Function	regulation of the secretion apparatus and of intra-membrane proteolysis
MW, pI	27 kDa, 5.635
Gene length, protein length	741 bp, 247 aa
Immediate neighbours	hit, ecsB
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU10040

Phenotypes of a mutant

no processing of RsiW and FtsL PubMed

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

Categories containing this gene/protein

ABC transporters, protein secretion, sigma factors and their control, membrane proteins

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: ABC transporter domain (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: EcsA-EcsB PubMed

• Localization: membrane associated (via EcsB) PubMed

Database entries

• Structure:

• UniProt: P55339

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information: the mRNA is very stable (half-life > 15 min) PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: