Difference between revisions of "PtsI"
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* '''Operon:''' ''[[ptsG]]-[[ptsH]]-[[ptsI]]'', ''[[ptsH]]-[[ptsI]]'' | * '''Operon:''' ''[[ptsG]]-[[ptsH]]-[[ptsI]]'', ''[[ptsH]]-[[ptsI]]'' | ||
| − | * '''Sigma factor:''' [[SigA]] | + | * '''Sigma factor:''' [[SigA]] [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=+11902727 PubMed] |
| − | |||
* '''Regulation:''' induction by glucose (''[[ptsG]]''), constitutive (''[[ptsH]]'') | * '''Regulation:''' induction by glucose (''[[ptsG]]''), constitutive (''[[ptsH]]'') | ||
Revision as of 11:38, 12 January 2009
- Description: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
| Gene name | ptsI |
| Synonyms | |
| Essential | no |
| Product | phosphotransferase system (PTS) enzyme I |
| Function | transfers phosphate from PEP to HPr |
| MW, pI | 62,9 kDa, 4.59 |
| Gene length, protein length | 1710 bp, 570 amino acids |
| Immediate neighbours | pstH, splA |
| Gene sequence (+200bp) | Protein sequence |
| Genetic context File:GenE context.gif | |
Contents
The gene
Basic information
- Coordinates:
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [[2]]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Phosphoenolpyruvate + protein L-histidine = pyruvate + protein N(pi)-phospho-L-histidine
- Protein family: PEP-utilizing enzyme family
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- HPr binding site (N-Terminal Domain)
- pyruvate binding site (C-Terminal Domain)
- pyrophosphate/phosphate carrier histidine (central Domain)
- Modification:
- Cofactor(s): Magnesium
- Effectors of protein activity:
- Interactions:
- Localization: Cytoplasm
Database entries
- Structure:
- Swiss prot entry: [3]
- KEGG entry: [4]
- E.C. number: [5]
Additional information
Expression and regulation
- Additional information:
Biological materials
Labs working on this gene/protein
Josef Deutscher, Paris-Grignon, France
Jörg Stülke, University of Göttingen, Germany Homepage
