Difference between revisions of "MhqA"
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* '''Protein family:''' extradiol ring-cleavage dioxygenase family (according to Swiss-Prot) | * '''Protein family:''' extradiol ring-cleavage dioxygenase family (according to Swiss-Prot) | ||
| − | * '''Paralogous protein(s):''' | + | * '''Paralogous protein(s):''' [[MhqE]], [[MhqO]] |
=== Extended information on the protein === | === Extended information on the protein === | ||
| Line 78: | Line 78: | ||
=== Database entries === | === Database entries === | ||
| − | * '''Structure:''' | + | * '''Structure:''' [http://www.rcsb.org/pdb/explore/explore.do?pdbId=3OAJ 3OAJ] ([[MhqO]], 34% identical residues) |
* '''UniProt:''' [http://www.uniprot.org/uniprot/O34689 O34689] | * '''UniProt:''' [http://www.uniprot.org/uniprot/O34689 O34689] | ||
Revision as of 12:59, 24 August 2010
- Description: hydroquinone-specific dioxygenase, confers resistence to methyl-hydroxyquinone
| Gene name | mhqA |
| Synonyms | ykcA |
| Essential | no |
| Product | hydroquinone-specific dioxygenase |
| Function | resistence to methyl-hydroxyquinone |
| MW, pI | 35 kDa, 5.404 |
| Gene length, protein length | 948 bp, 316 aa |
| Immediate neighbours | steT, ykcB |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU12870
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: extradiol ring-cleavage dioxygenase family (according to Swiss-Prot)
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- UniProt: O34689
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: mhqA PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Stefanie Töwe, Montira Leelakriangsak, Kazuo Kobayashi, Nguyen Van Duy, Michael Hecker, Peter Zuber, Haike Antelmann
The MarR-type repressor MhqR (YkvE) regulates multiple dioxygenases/glyoxalases and an azoreductase which confer resistance to 2-methylhydroquinone and catechol in Bacillus subtilis.
Mol Microbiol: 2007, 66(1);40-54
[PubMed:17725564]
[WorldCat.org]
[DOI]
(P p)
Van Duy Nguyen, Carmen Wolf, Ulrike Mäder, Michael Lalk, Peter Langer, Ulrike Lindequist, Michael Hecker, Haike Antelmann
Transcriptome and proteome analyses in response to 2-methylhydroquinone and 6-brom-2-vinyl-chroman-4-on reveal different degradation systems involved in the catabolism of aromatic compounds in Bacillus subtilis.
Proteomics: 2007, 7(9);1391-408
[PubMed:17407181]
[WorldCat.org]
[DOI]
(P p)
