Difference between revisions of "RecO"
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| − | * '''Description:''' mediator of RecA binding to ssDNA <br/><br/> | + | * '''Description:''' mediator of [[RecA]] binding to ssDNA <br/><br/> |
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
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| − | |style="background:#ABCDEF;" align="center"| '''Product''' || mediator of RecA binding to ssDNA | + | |style="background:#ABCDEF;" align="center"| '''Product''' || mediator of [[RecA]] binding to ssDNA |
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|style="background:#ABCDEF;" align="center"|'''Function''' || DNA repair and genetic recombination | |style="background:#ABCDEF;" align="center"|'''Function''' || DNA repair and genetic recombination | ||
Revision as of 10:23, 29 June 2010
- Description: mediator of RecA binding to ssDNA
| Gene name | recO |
| Synonyms | yqxN, yqfI |
| Essential | no |
| Product | mediator of RecA binding to ssDNA |
| Function | DNA repair and genetic recombination |
| MW, pI | 29 kDa, 8.208 |
| Gene length, protein length | 765 bp, 255 aa |
| Immediate neighbours | glyQ, era |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU25280
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: recO family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P42095
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Candela Manfredi, Yuki Suzuki, Tribhuwan Yadav, Kunio Takeyasu, Juan C Alonso
RecO-mediated DNA homology search and annealing is facilitated by SsbA.
Nucleic Acids Res: 2010, 38(20);6920-9
[PubMed:20581116]
[WorldCat.org]
[DOI]
(I p)
Dawit Kidane, Begoña Carrasco, Candela Manfredi, Katharina Rothmaier, Silvia Ayora, Serkalem Tadesse, Juan C Alonso, Peter L Graumann
Evidence for different pathways during horizontal gene transfer in competent Bacillus subtilis cells.
PLoS Genet: 2009, 5(9);e1000630
[PubMed:19730681]
[WorldCat.org]
[DOI]
(I p)
Candela Manfredi, Begoña Carrasco, Silvia Ayora, Juan C Alonso
Bacillus subtilis RecO nucleates RecA onto SsbA-coated single-stranded DNA.
J Biol Chem: 2008, 283(36);24837-47
[PubMed:18599486]
[WorldCat.org]
[DOI]
(P p)
