Difference between revisions of "CggR"
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[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] |
Revision as of 10:08, 23 April 2010
- Description: repressor of the glycolytic gapA operon, DeoR family
Gene name | cggR |
Synonyms | yvbQ |
Essential | no |
Product | central glycolytic genes regulator |
Function | transcriptional regulator |
Metabolic function and regulation of this protein in SubtiPathways: Central C-metabolism | |
MW, pI | 37,2 kDa,5.68 |
Gene length, protein length | 1020 bp, 340 amino acids |
Immediate neighbours | gapA, araE |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
|
Contents
The gene
Basic information
- Locus tag: BSU33950
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: transcription repression of the glycolytic gapA operon
- Protein family: sorC transcriptional regulatory family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- DNA binding domain (H-T-H motif) (37–56)
- Modification:
- Cofactor(s):
- Effectors of protein activity: fructose 1.6-bisphosphate PubMed and dihydroxyacetone phosphate, glucose-6-phosphate and fructose-6-phosphate PubMed act as inducer and result in release of CggR from the DNA
- Interactions:
- Localization:
Database entries
- Structure: 2OKG ( effector binding domain), 3BXH (in complex with fructose-6-phosphate), complex with Fructose-6-Phosphate NCBI, effector binding domain NCBI
- UniProt: O32253
- KEGG entry: [3]
Additional information
Expression and regulation
- Database entries: DBTBS
- Additional information:
Biological materials
- Mutant:
- GP311 (in frame deletion), available in Stülke lab
- SM-NB7 (cggR-spc), available in Anne Galinier's and Boris Görke's labs
- GFP fusion:
- Antibody: available in Stülke lab
Labs working on this gene/protein
Stephane Aymerich, Microbiology and Molecular Genetics, INRA Paris-Grignon, France
Your additional remarks
References
Reviews
Sabine Brantl, Andreas Licht
Characterisation of Bacillus subtilis transcriptional regulators involved in metabolic processes.
Curr Protein Pept Sci: 2010, 11(4);274-91
[PubMed:20408793]
[WorldCat.org]
[DOI]
(I p)
Original Publications