Difference between revisions of "BshB1"
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|style="background:#ABCDEF;" align="center"|'''Gene name''' | |style="background:#ABCDEF;" align="center"|'''Gene name''' | ||
| − | |'' | + | |''bshB1'' |
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|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''jojG, ypjG '' | |style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''jojG, ypjG '' | ||
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|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 672 bp, 224 aa | |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 672 bp, 224 aa | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ | + | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[bshA]]'', ''[[mgsA]]'' |
|- | |- | ||
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[EMBLCDS:CAB14163]+-newId sequences] <br/> (Barbe ''et al.'', 2009)''' | |colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[EMBLCDS:CAB14163]+-newId sequences] <br/> (Barbe ''et al.'', 2009)''' | ||
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=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' | + | * '''Operon:''' ''[[ypjD]]-[[dapB]]-[[mgsA]]-[[bshB1]]-[[bshA]]-[[cca]]-[[birA]]'' {{PubMed|20308541}} |
* '''[[Sigma factor]]:''' | * '''[[Sigma factor]]:''' | ||
Revision as of 10:20, 7 April 2010
- Description: N-acetyl hydrolase involved in bacillithiol synthesis
| Gene name | bshB1 |
| Synonyms | jojG, ypjG |
| Essential | no |
| Product | unknown |
| Function | unknown |
| Metabolic function and regulation of this protein in SubtiPathways: Lys, Thr | |
| MW, pI | 24 kDa, 6.343 |
| Gene length, protein length | 672 bp, 224 aa |
| Immediate neighbours | bshA, mgsA |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU22470
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: GlcNAc-Mal -> GlcN-Mal + Ac
- Protein family:
- Paralogous protein(s): BshB2
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: P42981
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant: bshB1 null mutant and bshB1 / bshB2 double null mutant available in John Helmann lab
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Ahmed Gaballa, Gerald L Newton, Haike Antelmann, Derek Parsonage, Heather Upton, Mamta Rawat, Al Claiborne, Robert C Fahey, John D Helmann
Biosynthesis and functions of bacillithiol, a major low-molecular-weight thiol in Bacilli.
Proc Natl Acad Sci U S A: 2010, 107(14);6482-6
[PubMed:20308541]
[WorldCat.org]
[DOI]
(I p)
