Difference between revisions of "GpsA"
Line 14: | Line 14: | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of phospholipids | |style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of phospholipids | ||
|- | |- | ||
− | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/ | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/fatty_acid_synthesis.html Lipid synthesis]''' |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 37 kDa, 6.231 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 37 kDa, 6.231 |
Revision as of 14:12, 7 March 2010
- Description: glycerol-3-phosphate dehydrogenase (NAD)
Gene name | gpsA |
Synonyms | |
Essential | yes PubMed |
Product | glycerol-3-phosphate dehydrogenase (NAD) |
Function | biosynthesis of phospholipids |
Metabolic function and regulation of this protein in SubtiPathways: Lipid synthesis | |
MW, pI | 37 kDa, 6.231 |
Gene length, protein length | 1035 bp, 345 aa |
Immediate neighbours | yphE, yphC |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
|
Contents
The gene
Basic information
- Locus tag: BSU22830
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: sn-glycerol 3-phosphate + NAD(P)+ = glycerone phosphate + NAD(P)H (according to Swiss-Prot)
- Protein family: NAD-dependent glycerol-3-phosphate dehydrogenase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- Structure: 3K96 (from Coxiella burnetii RSA 493, 37% identity, 59% similarity)
- UniProt: P46919
- KEGG entry: [2]
- E.C. number: 1.1.1.94
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
H R Morbidoni, D de Mendoza, J E Cronan
Synthesis of sn-glycerol 3-phosphate, a key precursor of membrane lipids, in Bacillus subtilis.
J Bacteriol: 1995, 177(20);5899-905
[PubMed:7592341]
[WorldCat.org]
[DOI]
(P p)