Difference between revisions of "PurH"
(→Database entries) |
|||
Line 80: | Line 80: | ||
=== Database entries === | === Database entries === | ||
− | * '''Structure:''' | + | * '''Structure:''' [http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1ZCZ 1ZCZ] (from ''Thermotoga maritima'', 36% identity, 54% similarity) {{PubMed|18260100}} |
* '''UniProt:''' [http://www.uniprot.org/uniprot/P12048 P12048] | * '''UniProt:''' [http://www.uniprot.org/uniprot/P12048 P12048] |
Revision as of 14:02, 19 February 2010
- Description: phosphoribosylaminoimidazole carboxamide formyltransferase
Gene name | purH |
Synonyms | purJ |
Essential | no |
Product | phosphoribosylaminoimidazole carboxamide formyltransferase and inosine-monophosphate cyclohydrolase |
Function | purine biosynthesis |
Metabolic function and regulation of this protein in SubtiPathways: Purine synthesis, Nucleotides (regulation) | |
MW, pI | 55 kDa, 5.133 |
Gene length, protein length | 1536 bp, 512 aa |
Immediate neighbours | purN, purD |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
|
Contents
The gene
Basic information
- Locus tag: BSU06520
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: 10-formyltetrahydrofolate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide = tetrahydrofolate + 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide (according to Swiss-Prot)
- Protein family: purH family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- UniProt: P12048
- KEGG entry: [3]
- E.C. number: 2.1.2.3
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References