Difference between revisions of "MetA"
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=== Database entries === | === Database entries === | ||
− | * '''Structure:''' | + | * '''Structure:''' [http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2GHR 2GHR] (from ''Bacillus cereus'', 60% identity, 77% similarity) {{PubMed|17546672}} |
* '''UniProt:''' [http://www.uniprot.org/uniprot/P54167 P54167] | * '''UniProt:''' [http://www.uniprot.org/uniprot/P54167 P54167] |
Revision as of 15:23, 18 February 2010
- Description: homoserine O-succinyltransferase
Gene name | metA |
Synonyms | metB |
Essential | no |
Product | homoserine O-succinyltransferase |
Function | biosynthesis of methionine |
Metabolic function and regulation of this protein in SubtiPathways: Lys, Thr, Cys, Met & Sulfate assimilation | |
MW, pI | 25 kDa, 6.414 |
Gene length, protein length | 672 bp, 224 aa |
Immediate neighbours | bsaA, ugtP |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
|
Contents
The gene
Basic information
- Locus tag: BSU21910
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Succinyl-CoA + L-homoserine = CoA + O-succinyl-L-homoserine (according to Swiss-Prot) O(4)-succinyl-L-homoserine + L-cysteine = L-cystathionine + succinate (according to Swiss-Prot)
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- UniProt: P54167
- KEGG entry: [3]
- E.C. number: 2.3.1.46 8 2.5.1.48]
Additional information
Expression and regulation
- Operon: metA (according to DBTBS)
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody: