Difference between revisions of "ValS"
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− | * '''Structure:''' | + | * '''Structure:''' [http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1IYW 1IYW] (from ''Thermus thermophilus'', 41% identity, 60% similarity) {{PubMed|12554880}} |
* '''UniProt:''' [http://www.uniprot.org/uniprot/Q05873 Q05873] | * '''UniProt:''' [http://www.uniprot.org/uniprot/Q05873 Q05873] |
Revision as of 14:42, 18 February 2010
- Description: valyl-tRNA synthetase
Gene name | valS |
Synonyms | |
Essential | yes PubMed |
Product | valyl-tRNA synthetase |
Function | translation |
Metabolic function and regulation of this protein in SubtiPathways: tRNA charging, Folate | |
MW, pI | 101 kDa, 4.868 |
Gene length, protein length | 2640 bp, 880 aa |
Immediate neighbours | folC, ysxE |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
|
Contents
The gene
Basic information
- Locus tag: BSU28090
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP + L-valine + tRNA(Val) = AMP + diphosphate + L-valyl-tRNA(Val) (according to Swiss-Prot)
- Protein family: ValS type 1 subfamily (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- UniProt: Q05873
- KEGG entry: [3]
- E.C. number: 6.1.1.9
Additional information
Expression and regulation
- Regulatory mechanism:
- T-box: riboswitch, transcription termination/antitermination PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Original Publications
D Luo, J Leautey, M Grunberg-Manago, H Putzer
Structure and regulation of expression of the Bacillus subtilis valyl-tRNA synthetase gene.
J Bacteriol: 1997, 179(8);2472-8
[PubMed:9098041]
[WorldCat.org]
[DOI]
(P p)