Difference between revisions of "Tpi"
(→Extended information on the protein) |
(→Expression and regulation) |
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=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' ''[[cggR]] [[gapA]] [[pgk]] | + | * '''Operon:''' |
| + | ** ''[[cggR]]-[[gapA]]-[[pgk]]-[[tpiA]]-[[pgm]]-[[eno]]'' | ||
| + | ** ''[[cggR]]-[[gapA]]'' | ||
* '''Sigma factor:''' [[SigA]] | * '''Sigma factor:''' [[SigA]] | ||
Revision as of 14:31, 9 January 2009
- Description: catalyzes the transformation of glycerinaldehyd 3-phosphate to dihydroxyactonphosphate and the reverse reaktion
| Gene name | tpi |
| Synonyms | tpiA |
| Essential | yes |
| Product | Triosephosphate isomerase |
| Function | isomerase |
| MW, pI | 26,9 kDa, 4.79 |
| Gene length, protein length | 759 bp, 253 amino acids |
| Immediate neighbours | pgk, pgm |
| Gene sequence (+200bp) | Protein sequence |
| Genetic context File:GenE context.gif | |
Contents
The gene
Basic information
- Coordinates:
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: D-glyceraldehyde 3-phosphate = glycerone phosphate
- Protein family: triosephosphate isomerase family
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification: phosphorylation PubMed
- Cofactor(s):
- Effectors of protein activity:
- Interactions: Pgm-TpiA
- Localization: cytoplasm PubMed
Database entries
- Structure: complex with 2-phosphpoglycolic acid, Geobacillus stearothermophilus NCBI
- Swiss prot entry: [3]
- KEGG entry: [4]
- E.C. number: [5]
Additional information
Expression and regulation
- Sigma factor: SigA
- Additional information:
Biological materials
Labs working on this gene/protein
Your additional remarks
References
- Ludwig, H., Homuth, G., Schmalisch, M., Dyka, F. M., Hecker, M., and Stülke, J. (2001) Transcription of glycolytic genes and operons in Bacillus subtilis: evidence for the presence of multiple levels of control of the gapA operon. Mol Microbiol 41, 409-422.PubMed
