Difference between revisions of "SufU"
| Line 1: | Line 1: | ||
| − | * '''Description:''' synthesis von Fe-S clusters <br/><br/> | + | * '''Description:''' iron-sulfur cluster scaffold protein, synthesis von Fe-S clusters <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Gene name''' | |style="background:#ABCDEF;" align="center"|'''Gene name''' | ||
| − | |'' | + | |''sufU'' |
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yurV'' | + | |style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yurV, iscU'' |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''Essential''' || yes [http://www.ncbi.nlm.nih.gov/pubmed/12682299 PubMed] | |style="background:#ABCDEF;" align="center"| '''Essential''' || yes [http://www.ncbi.nlm.nih.gov/pubmed/12682299 PubMed] | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Product''' || | + | |style="background:#ABCDEF;" align="center"| '''Product''' || iron-sulfur cluster scaffold protein |
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Function''' || | + | |style="background:#ABCDEF;" align="center"|'''Function''' || synthesis of iron-sulfur clusters |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 16 kDa, 4.713 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 16 kDa, 4.713 | ||
| Line 18: | Line 18: | ||
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 441 bp, 147 aa | |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 441 bp, 147 aa | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ | + | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[sufB]]'', ''[[sufS]]'' |
|- | |- | ||
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[EMBLCDS:CAB15257]+-newId sequences] <br/> (Barbe ''et al.'', 2009)''' | |colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[EMBLCDS:CAB15257]+-newId sequences] <br/> (Barbe ''et al.'', 2009)''' | ||
| Line 72: | Line 72: | ||
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
| − | * '''Interactions:''' ([[YdhG]])2-[[IscU]], requires iron {{PubMed|20087498}} | + | * '''Interactions:''' ([[YdhG]])2-[[IscU]], requires iron {{PubMed|20087498}}, [[SufS]]-[[SufU]] {{PubMed|20097860}} |
* '''Localization:''' | * '''Localization:''' | ||
| Line 119: | Line 119: | ||
=References= | =References= | ||
| − | <pubmed> 20087498 </pubmed> | + | <pubmed> 20087498 20097860 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 11:10, 26 January 2010
- Description: iron-sulfur cluster scaffold protein, synthesis von Fe-S clusters
| Gene name | sufU |
| Synonyms | yurV, iscU |
| Essential | yes PubMed |
| Product | iron-sulfur cluster scaffold protein |
| Function | synthesis of iron-sulfur clusters |
| MW, pI | 16 kDa, 4.713 |
| Gene length, protein length | 441 bp, 147 aa |
| Immediate neighbours | sufB, sufS |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU32680
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: nifU family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
Database entries
- Structure: 2AZH
- UniProt: O32163
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Alexander G Albrecht, Daili J A Netz, Marcus Miethke, Antonio J Pierik, Olaf Burghaus, Florian Peuckert, Roland Lill, Mohamed A Marahiel
SufU is an essential iron-sulfur cluster scaffold protein in Bacillus subtilis.
J Bacteriol: 2010, 192(6);1643-51
[PubMed:20097860]
[WorldCat.org]
[DOI]
(I p)
Wenbin Qi, J A Cowan
A structural and functional homolog supports a general role for frataxin in cellular iron chemistry.
Chem Commun (Camb): 2010, 46(5);719-21
[PubMed:20087498]
[WorldCat.org]
[DOI]
(I p)
