Difference between revisions of "FadE"
| Line 89: | Line 89: | ||
* '''Operon:''' | * '''Operon:''' | ||
| + | ** ''[[fadM]]-[[fadN]]-[[fadA]]-[[fadE]]'' {{PubMed|17189250}} | ||
| + | ** ''[[fadN]]-[[fadA]]-[[fadE]]'' {{PubMed|17189250}} | ||
* '''[[Sigma factor]]:''' | * '''[[Sigma factor]]:''' | ||
| + | ** ''[[fadN]]'': [[SigA]] {{PubMed|17189250}} | ||
* '''Regulation:''' | * '''Regulation:''' | ||
| − | ** | + | ** ''[[fadN]]'': induced by long-chain fatty acids ([[FadR]]) {{PubMed|17189250}} |
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| − | ** [[FadR]]: transcription repression [ | + | ** [[FadR]]: transcription repression {{PubMed|17189250}} |
| + | ** [[SdpR]]: transcription activation {{PubMed|12817086}} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
| Line 120: | Line 124: | ||
=References= | =References= | ||
| − | <pubmed>17189250, | + | <pubmed>17189250,12817086 ,</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 16:26, 28 December 2009
- Description: acyl-CoA dehydrogenase
| Gene name | fadE |
| Synonyms | yusJ |
| Essential | no |
| Product | acyl-CoA dehydrogenase |
| Function | fatty acid degradation |
| MW, pI | 65 kDa, 5.146 |
| Gene length, protein length | 1782 bp, 594 aa |
| Immediate neighbours | yusI, fadA |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU32820
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Acyl-CoA + ETF = 2,3-dehydroacyl-CoA + reduced ETF (according to Swiss-Prot)
- Protein family: acyl-CoA dehydrogenase family (according to Swiss-Prot)
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: O32176
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
