Difference between revisions of "ThrC"

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(Expression and regulation)
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=Expression and regulation=
 
=Expression and regulation=
 
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* '''Operon:''' ''[[hom]]-[[thrC]]-[[thrB]]'' {{PubMed|12107147}}
* '''Operon:''' ''[[hom]]-[[thrC]]-[[thrB]]''
 
  
 
* '''[[Sigma factor]]:'''  
 
* '''[[Sigma factor]]:'''  
  
* '''Regulation:''' repressed by casamino acids [http://www.ncbi.nlm.nih.gov/pubmed/12107147 PubMed]  
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* '''Regulation:'''  
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** repressed by casamino acids {{PubMed|12107147}}  
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  

Revision as of 10:00, 28 December 2009

  • Description: threonine synthase

Gene name thrC
Synonyms thrB
Essential no
Product threonine synthase
Function biosynthesis of threonine
Metabolic function and regulation of this protein in SubtiPathways:
Lys, Thr
MW, pI 37 kDa, 5.185
Gene length, protein length 1056 bp, 352 aa
Immediate neighbours thrB, hom
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
ThrC context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU32250

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: O-phospho-L-homoserine + H2O = L-threonine + phosphate (according to Swiss-Prot)
  • Protein family: serine/threonine dehydratase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Regulation:
    • repressed by casamino acids PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References