Difference between revisions of "InfC"

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=Expression and regulation=
 
=Expression and regulation=
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* '''Operon:''' ''[[infC]]-[[rpmI]]-[[rplT]]-[[ysdA]]'' {{PubMed|17289755}}
  
* '''Operon:'''
+
* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|17289755}}
 
 
* '''[[Sigma factor]]:'''  
 
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
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* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
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** binding of [[RplT]] to a RNA site in the ''[[infC]]'' leader region causes transcription termination {{PubMed|17289755}}
  
 
* '''Additional information:'''  
 
* '''Additional information:'''  
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=References=
 
=References=
 
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<pubmed>17289755 11948165 </pubmed>
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 20:22, 17 December 2009

  • Description: translation initiation factor IF-3

Gene name infC
Synonyms
Essential yes PubMed
Product initiation factor IF-3
Function translation
MW, pI 19 kDa, 10.342
Gene length, protein length 519 bp, 173 aa
Immediate neighbours rpmI, yscA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
InfC context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU28870

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: IF-3 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure: 1TIF (N-terminal domain, Geobacillus stearothermophilus), 1TIG (C-terminal domain, Geobacillus stearothermophilus)
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • RelA dependent downregulation (Class I) during stringent response PubMed
  • Regulatory mechanism:
    • binding of RplT to a RNA site in the infC leader region causes transcription termination PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References