Difference between revisions of "GerM"

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=Expression and regulation=
 
=Expression and regulation=
  
* '''Operon:'''  
+
* '''Operon:''' ''gerM'' {{PubMed|8969504}}
  
* '''[[Sigma factor]]:''' [[SigE]] {{PubMed|15699190}}
+
* '''[[Sigma factor]]:''' [[SigE]] {{PubMed|8969504,15699190}}
  
* '''Regulation:''' repressed by casamino acids [http://www.ncbi.nlm.nih.gov/pubmed/12107147 PubMed]   
+
* '''Regulation:'''  
 +
** expressed early during sporulation in the mother cell ([[SigE]], [[SpoIIID]]) {{PubMed|8969504,15699190,15383836}}
 +
** repressed by casamino acids [http://www.ncbi.nlm.nih.gov/pubmed/12107147 PubMed]   
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
 +
** [[SpoIIID]]: transcription repression {{PubMed|15383836}}
  
 
* '''Additional information:'''  
 
* '''Additional information:'''  
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=References=
 
=References=
  
<pubmed>7926687,,12107147, </pubmed>
+
<pubmed>7926687,15699190,12107147, 8969504,15699190,15383836</pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 20:40, 13 December 2009

  • Description: germination (cortex hydrolysis) and sporulation

Gene name gerM
Synonyms
Essential no
Product unknown
Function germination (cortex hydrolysis) and sporulation
MW, pI 39 kDa, 4.683
Gene length, protein length 1098 bp, 366 aa
Immediate neighbours rph, racE
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
GerM context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU28380

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Leif Steil, Mónica Serrano, Adriano O Henriques, Uwe Völker
Genome-wide analysis of temporally regulated and compartment-specific gene expression in sporulating cells of Bacillus subtilis.
Microbiology (Reading): 2005, 151(Pt 2);399-420
[PubMed:15699190] [WorldCat.org] [DOI] (P p)

Patrick Eichenberger, Masaya Fujita, Shane T Jensen, Erin M Conlon, David Z Rudner, Stephanie T Wang, Caitlin Ferguson, Koki Haga, Tsutomu Sato, Jun S Liu, Richard Losick
The program of gene transcription for a single differentiating cell type during sporulation in Bacillus subtilis.
PLoS Biol: 2004, 2(10);e328
[PubMed:15383836] [WorldCat.org] [DOI] (I p)

Ulrike Mäder, Georg Homuth, Christian Scharf, Knut Büttner, Rüdiger Bode, Michael Hecker
Transcriptome and proteome analysis of Bacillus subtilis gene expression modulated by amino acid availability.
J Bacteriol: 2002, 184(15);4288-95
[PubMed:12107147] [WorldCat.org] [DOI] (P p)

A Wipat, N Carter, S C Brignell, B J Guy, K Piper, J Sanders, P T Emmerson, C R Harwood
The dnaB-pheA (256 degrees-240 degrees) region of the Bacillus subtilis chromosome containing genes responsible for stress responses, the utilization of plant cell walls and primary metabolism.
Microbiology (Reading): 1996, 142 ( Pt 11);3067-78
[PubMed:8969504] [WorldCat.org] [DOI] (P p)

G M Slynn, R L Sammons, D A Smith, A Moir, B M Corfe
Molecular genetical and phenotypical analysis of the gerM spore germination gene of Bacillus subtilis 168.
FEMS Microbiol Lett: 1994, 121(3);315-20
[PubMed:7926687] [WorldCat.org] [DOI] (P p)