Difference between revisions of "ComC"
| Line 90: | Line 90: | ||
=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' | + | * '''Operon:''' ''comS'' {{PubMed|1694528}} |
| − | * '''[[Sigma factor]]:''' | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|1694528}} |
* '''Regulation:''' | * '''Regulation:''' | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| + | ** ComK: transcription activation {{PubMed|8196543}} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
| Line 120: | Line 121: | ||
=References= | =References= | ||
| − | <pubmed>9723928,16751195,7783624,2553669,, </pubmed> | + | <pubmed>9723928,16751195,7783624,2553669,1694528, 8196543 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 19:37, 13 December 2009
- Description: late competence gene required for processing and translocation of ComGC, ComGD, ComGE and ComGG PubMed
| Gene name | comC |
| Synonyms | |
| Essential | no |
| Product | processing protease |
| Function | genetic transformation |
| MW, pI | 26 kDa, 9.843 |
| Gene length, protein length | 744 bp, 248 aa |
| Immediate neighbours | spoIIB, folC |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU28070
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Typically cleaves a -Gly-|-Phe- bond to release an N-terminal, basic peptide of 5-8 residues from type IV prepilin, and then N-methylates the new N-terminal amino group, the methyl donor being S-adenosyl-L-methionine (according to Swiss-Prot)
- Protein family: peptidase A24 family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P15378
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: comS PubMed
- Regulation:
- Regulatory mechanism:
- ComK: transcription activation PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
