Difference between revisions of "PhrF"
| Line 1: | Line 1: | ||
| − | * '''Description:''' phosphatase (RapF) regulator <br/><br/> | + | * '''Description:''' phosphatase ([[RapF]]) regulator <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
| Line 10: | Line 10: | ||
|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Product''' || phosphatase (RapF) regulator | + | |style="background:#ABCDEF;" align="center"| '''Product''' || phosphatase ([[RapF]]) regulator |
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Function''' || control of | + | |style="background:#ABCDEF;" align="center"|'''Function''' || control of [[ComA]] activity |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 4 kDa, 10.237 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 4 kDa, 10.237 | ||
| Line 52: | Line 52: | ||
=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
| − | * '''Catalyzed reaction/ biological activity:''' | + | * '''Catalyzed reaction/ biological activity:''' binds to [[RapF]], this results in the inability of [[RapF]] to interact with [[ComA]] {{PubMed|15968044}} |
* '''Protein family:''' phr family (according to Swiss-Prot) | * '''Protein family:''' phr family (according to Swiss-Prot) | ||
| Line 70: | Line 70: | ||
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
| − | * '''Interactions:''' | + | * '''Interactions:''' [[RapF]]-[[PhrF]] {{PubMed|15968044}} |
* '''Localization:''' | * '''Localization:''' | ||
| Line 118: | Line 118: | ||
=References= | =References= | ||
| − | <pubmed>16816200,, </pubmed> | + | <pubmed>16816200,15968044, </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 08:17, 29 November 2009
- Description: phosphatase (RapF) regulator
| Gene name | phrF |
| Synonyms | ywhI |
| Essential | no |
| Product | phosphatase (RapF) regulator |
| Function | control of ComA activity |
| MW, pI | 4 kDa, 10.237 |
| Gene length, protein length | 117 bp, 39 aa |
| Immediate neighbours | rapF, ywhH |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU37470
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: binds to RapF, this results in the inability of RapF to interact with ComA PubMed
- Protein family: phr family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
Database entries
- Structure:
- UniProt: P71001
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Jennifer M Auchtung, Catherine A Lee, Alan D Grossman
Modulation of the ComA-dependent quorum response in Bacillus subtilis by multiple Rap proteins and Phr peptides.
J Bacteriol: 2006, 188(14);5273-85
[PubMed:16816200]
[WorldCat.org]
[DOI]
(P p)
Cristina Bongiorni, Shu Ishikawa, Sophie Stephenson, Naotake Ogasawara, Marta Perego
Synergistic regulation of competence development in Bacillus subtilis by two Rap-Phr systems.
J Bacteriol: 2005, 187(13);4353-61
[PubMed:15968044]
[WorldCat.org]
[DOI]
(P p)
