Difference between revisions of "LutR"
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
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| − | |style="background:#ABCDEF;" align="center"| '''Product''' || transcriptional repressor | + | |style="background:#ABCDEF;" align="center"| '''Product''' || transcriptional repressor, ([[GntR family]]) |
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|style="background:#ABCDEF;" align="center"|'''Function''' || control of lactate utilization | |style="background:#ABCDEF;" align="center"|'''Function''' || control of lactate utilization | ||
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* '''Catalyzed reaction/ biological activity:''' transcriptional repressor of the'' [[lutA]]-[[lutB]]-[[lutC]]'' operon [http://www.ncbi.nlm.nih.gov/sites/entrez/19201793 PubMed] | * '''Catalyzed reaction/ biological activity:''' transcriptional repressor of the'' [[lutA]]-[[lutB]]-[[lutC]]'' operon [http://www.ncbi.nlm.nih.gov/sites/entrez/19201793 PubMed] | ||
| − | * '''Protein family:''' GntR family of transcription factors | + | * '''Protein family:''' [[GntR family]] of transcription factors |
* '''Paralogous protein(s):''' | * '''Paralogous protein(s):''' | ||
Revision as of 19:12, 27 November 2009
| Gene name | lutR |
| Synonyms | yvfI |
| Essential | no |
| Product | transcriptional repressor, (GntR family) |
| Function | control of lactate utilization |
| Metabolic function and regulation of this protein in SubtiPathways: Central C-metabolism | |
| MW, pI | 19 kDa, 4.845 |
| Gene length, protein length | 525 bp, 175 aa |
| Immediate neighbours | lacR, lutP |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU34180
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: transcriptional repressor of the lutA-lutB-lutC operon PubMed
- Protein family: GntR family of transcription factors
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity: lactate acts as molecular inducer PubMed
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: O07007
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Richard Losick, Harvard Univ., Cambridge, USA homepage
Your additional remarks
References
Yunrong Chai, Roberto Kolter, Richard Losick
A widely conserved gene cluster required for lactate utilization in Bacillus subtilis and its involvement in biofilm formation.
J Bacteriol: 2009, 191(8);2423-30
[PubMed:19201793]
[WorldCat.org]
[DOI]
(I p)
Türkan Ebru Köroğlu, Günseli Kurt-Gür, Emine Canan Unlü, Ayten Yazgan-Karataş
The novel gene yvfI in Bacillus subtilis is essential for bacilysin biosynthesis.
Antonie Van Leeuwenhoek: 2008, 94(3);471-9
[PubMed:18604637]
[WorldCat.org]
[DOI]
(P p)
