Difference between revisions of "YvrI"

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* '''Kinetic information:'''
 
* '''Kinetic information:'''
  
* '''Domains:'''  
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* '''Domains:''' contains a DNA-binding helix-turn-helix motif (HTH) and the region 4.2 of Sigma factors {{PubMed|19940246}}
  
 
* '''Modification:'''
 
* '''Modification:'''
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* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
  
* '''Interactions:''' [[YvrI]]-[[YvrHa]], [[YvrI]]-[[YvrHa]] [http://www.ncbi.nlm.nih.gov/sites/entrez/19047353 PubMed]
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* '''Interactions:''' [[YvrI]]-[[RpoB]] {{PubMed|19940246}},   [[YvrI]]-[[YvrHa]] {{PubMed|19940246}}
  
 
* '''Localization:'''
 
* '''Localization:'''
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=References=
 
=References=
  
<pubmed>18573182,,19047353,19047353 16306698, </pubmed>
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<pubmed>18573182,,19047353,19047353 16306698, 19940246 </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 09:00, 27 November 2009

Gene name yvrI
Synonyms sigO
Essential no
Product co-sigma factor with YvrHa
Function RNA polymerase sigma factor
MW, pI 20.76 kDa, 9.36
Gene length, protein length 531 bp, 176 aa
Immediate neighbours yvrHa, yvrJ
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YvrI context.gif
This image was kindly provided by SubtiList





The gene

Basic information

  • Locus tag: BSU33230

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains: contains a DNA-binding helix-turn-helix motif (HTH) and the region 4.2 of Sigma factors PubMed
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation: induced by acidic growth conditions PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

John Helmann, Cornell University, USA Homepage

Your additional remarks

References

Shawn R MacLellan, Veronica Guariglia-Oropeza, Ahmed Gaballa, John D Helmann
A two-subunit bacterial sigma-factor activates transcription in Bacillus subtilis.
Proc Natl Acad Sci U S A: 2009, 106(50);21323-8
[PubMed:19940246] [WorldCat.org] [DOI] (I p)

Shawn R MacLellan, John D Helmann, Haike Antelmann
The YvrI alternative sigma factor is essential for acid stress induction of oxalate decarboxylase in Bacillus subtilis.
J Bacteriol: 2009, 191(3);931-9
[PubMed:19047353] [WorldCat.org] [DOI] (I p)

Shawn R MacLellan, Tina Wecke, John D Helmann
A previously unidentified sigma factor and two accessory proteins regulate oxalate decarboxylase expression in Bacillus subtilis.
Mol Microbiol: 2008, 69(4);954-67
[PubMed:18573182] [WorldCat.org] [DOI] (I p)

Masakuni Serizawa, Keisuke Kodama, Hiroki Yamamoto, Kazuo Kobayashi, Naotake Ogasawara, Junichi Sekiguchi
Functional analysis of the YvrGHb two-component system of Bacillus subtilis: identification of the regulated genes by DNA microarray and northern blot analyses.
Biosci Biotechnol Biochem: 2005, 69(11);2155-69
[PubMed:16306698] [WorldCat.org] [DOI] (P p)