Difference between revisions of "FatR"
| Line 1: | Line 1: | ||
| − | * '''Description:''' transcriptional repressor of the fatR-yrhJ operon <br/><br/> | + | * '''Description:''' transcriptional repressor of the ''[[fatR]]-[[yrhJ]]'' operon <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
| Line 10: | Line 10: | ||
|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Product''' || transcriptional repressor <br/>of the fatR yrhJ operon (TetR family) | + | |style="background:#ABCDEF;" align="center"| '''Product''' || transcriptional repressor <br/>of the ''[[fatR]]-[[yrhJ]]'' operon (TetR family) |
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || unknown | |style="background:#ABCDEF;" align="center"|'''Function''' || unknown | ||
| Line 88: | Line 88: | ||
=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' ''[[fatR]]-[[yrhJ]]'' | + | * '''Operon:''' ''[[fatR]]-[[yrhJ]]'' {{PubMed|10917605}} |
| − | * '''[[Sigma factor]]:''' [[ | + | * '''[[Sigma factor]]:''' [[SigM]] {{PubMed|12775685}} |
| − | * '''Regulation:''' induced by unsaturated fatty acids ([[FatR]]) | + | * '''Regulation:''' |
| + | ** induced by unsaturated fatty acids ([[FatR]]) {{PubMed|11734890}} | ||
| − | * '''Regulatory mechanism:''' [[FatR]]: transcription repression | + | * '''Regulatory mechanism:''' |
| + | ** [[FatR]]: transcription repression {{PubMed|11734890}} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
| Line 118: | Line 120: | ||
=References= | =References= | ||
| − | <pubmed>11734890,11574077,11377867,, </pubmed> | + | <pubmed>11734890,11574077,11377867,10917605, 12775685</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 20:57, 25 November 2009
| Gene name | fatR |
| Synonyms | yrhI, bscR |
| Essential | no |
| Product | transcriptional repressor of the fatR-yrhJ operon (TetR family) |
| Function | unknown |
| MW, pI | 22 kDa, 5.621 |
| Gene length, protein length | 582 bp, 194 aa |
| Immediate neighbours | yrhJ, yrhH |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU27170
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: O08335
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Penny D Thackray, Anne Moir
SigM, an extracytoplasmic function sigma factor of Bacillus subtilis, is activated in response to cell wall antibiotics, ethanol, heat, acid, and superoxide stress.
J Bacteriol: 2003, 185(12);3491-8
[PubMed:12775685]
[WorldCat.org]
[DOI]
(P p)
M C Gustafsson, C N Palmer, C R Wolf, C von Wachenfeldt
Fatty-acid-displaced transcriptional repressor, a conserved regulator of cytochrome P450 102 transcription in Bacillus species.
Arch Microbiol: 2001, 176(6);459-64
[PubMed:11734890]
[WorldCat.org]
[DOI]
(P p)
T R Lee, H P Hsu, G C Shaw
Transcriptional regulation of the Bacillus subtilis bscR-CYP102A3 operon by the BscR repressor and differential induction of cytochrome CYP102A3 expression by oleic acid and palmitate.
J Biochem: 2001, 130(4);569-74
[PubMed:11574077]
[WorldCat.org]
[DOI]
(P p)
M C Gustafsson, C von Wachenfeldt
A novel diffusible substance can overcome the apparent AbrB repression of the Bacillus subtilis fatR promoter.
FEMS Microbiol Lett: 2001, 199(2);197-202
[PubMed:11377867]
[WorldCat.org]
[DOI]
(P p)
C N Palmer, M C Gustafsson, H Dobson, C von Wachenfeldt, C R Wolf
Adaptive responses to fatty acids are mediated by the regulated expression of cytochromes P450.
Biochem Soc Trans: 1999, 27(4);374-8
[PubMed:10917605]
[WorldCat.org]
[DOI]
(P p)
