Difference between revisions of "MtlA"
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| − | * '''Description:''' [[trigger enzymes|trigger enzyme]]: mannitol-specific phosphotransferase system, EIICB <br/><br/> | + | * '''Description:''' [[trigger enzymes|trigger enzyme]]: mannitol-specific [[PTS|phosphotransferase system]], EIICB of the [[PTS]]<br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Product''' || [[trigger enzymes|trigger enzyme]]: mannitol-specific phosphotransferase system, EIICB | + | |style="background:#ABCDEF;" align="center"| '''Product''' || [[trigger enzymes|trigger enzyme]]: mannitol-specific [[PTS|phosphotransferase system]], EIICB |
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || mannitol uptake and phosphorylation, control of [[MtlR]] activity | |style="background:#ABCDEF;" align="center"|'''Function''' || mannitol uptake and phosphorylation, control of [[MtlR]] activity | ||
| Line 58: | Line 58: | ||
* '''Catalyzed reaction/ biological activity:''' Protein EIIA N(pi)-phospho-L-histidine + protein EIIB = protein EIIA + protein EIIB N(pi)-phospho-L-histidine/cysteine (according to Swiss-Prot) | * '''Catalyzed reaction/ biological activity:''' Protein EIIA N(pi)-phospho-L-histidine + protein EIIB = protein EIIA + protein EIIB N(pi)-phospho-L-histidine/cysteine (according to Swiss-Prot) | ||
| − | * '''Protein family:''' PTS permease, fructose/ mannitol permease (Fru) family [http://www.ncbi.nlm.nih.gov/pubmed/10627040 PubMed] | + | * '''Protein family:''' [[PTS]] permease, fructose/ mannitol permease (Fru) family [http://www.ncbi.nlm.nih.gov/pubmed/10627040 PubMed] |
* '''Paralogous protein(s):''' | * '''Paralogous protein(s):''' | ||
Revision as of 19:11, 24 November 2009
- Description: trigger enzyme: mannitol-specific phosphotransferase system, EIICB of the PTS
| Gene name | mtlA |
| Synonyms | |
| Essential | no |
| Product | trigger enzyme: mannitol-specific phosphotransferase system, EIICB |
| Function | mannitol uptake and phosphorylation, control of MtlR activity |
| Metabolic function and regulation of this protein in SubtiPathways: Sugar catabolism | |
| MW, pI | 65 kDa, 8.778 |
| Gene length, protein length | 1830 bp, 610 aa |
| Immediate neighbours | ycnL, mtlF |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU03981
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Protein EIIA N(pi)-phospho-L-histidine + protein EIIB = protein EIIA + protein EIIB N(pi)-phospho-L-histidine/cysteine (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification: phosphorylation on Ser-559 PubMed
- Cofactor(s):
- Effectors of protein activity:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P42956
- KEGG entry: [3]
- E.C. number: 2.7.1.69
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
