Difference between revisions of "GcvPB"

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(Expression and regulation)
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* '''Regulation:''' repressed by casamino acids [http://www.ncbi.nlm.nih.gov/pubmed/12107147 PubMed] ,  induced by glycine [http://www.ncbi.nlm.nih.gov/sites/entrez/15472076 PubMed]
 
* '''Regulation:''' repressed by casamino acids [http://www.ncbi.nlm.nih.gov/pubmed/12107147 PubMed] ,  induced by glycine [http://www.ncbi.nlm.nih.gov/sites/entrez/15472076 PubMed]
  
* '''Regulatory mechanism:''' induction requires a co-operatively acting riboswitch [http://www.ncbi.nlm.nih.gov/sites/entrez/15472076 PubMed]
+
* '''Regulatory mechanism:'''  
 +
** induction requires a co-operatively acting [[riboswitch]] ([[G-box]])[http://www.ncbi.nlm.nih.gov/sites/entrez/15472076 PubMed]
  
 
* '''Additional information:'''
 
* '''Additional information:'''

Revision as of 20:25, 20 November 2009

  • Description: glycine decarboxylase (subunit 2)

Gene name gcvPB
Synonyms yqhK, gcvP
Essential no
Product glycine decarboxylase (subunit 2)
Function glycine utilization
MW, pI 54 kDa, 5.283
Gene length, protein length 1464 bp, 488 aa
Immediate neighbours yqhL, gcvPA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
GcvPB context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU24550

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Glycine + H-protein-lipoyllysine = H-protein-S-aminomethyldihydrolipoyllysine + CO2 (according to Swiss-Prot)
  • Protein family: C-terminal subunit subfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: membrane (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation: repressed by casamino acids PubMed , induced by glycine PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References