Difference between revisions of "AlsR"
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| − | * '''Description:''' transcriptional activator of the '' | + | * '''Description:''' transcriptional activator of the ''[[alsS]]-[[alsD]]'' operon<br/><br/> |
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
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| − | |style="background:#ABCDEF;" align="center"| '''Product''' || transcriptional activator(LysR family) | + | |style="background:#ABCDEF;" align="center"| '''Product''' || transcriptional activator([[LysR family]]) |
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| − | |style="background:#ABCDEF;" align="center"|'''Function''' || regulation of acetoin synthesis ('' | + | |style="background:#ABCDEF;" align="center"|'''Function''' || regulation of acetoin synthesis (''[[alsS]]-[[alsD]]'') |
|- | |- | ||
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/carbon_flow.html Central C-metabolism]''' | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/carbon_flow.html Central C-metabolism]''' | ||
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* '''Catalyzed reaction/ biological activity:''' binds the promoter region of the ''[[alsS]]-[[alsD]]'' operon in the presence of acetate, activates transcription | * '''Catalyzed reaction/ biological activity:''' binds the promoter region of the ''[[alsS]]-[[alsD]]'' operon in the presence of acetate, activates transcription | ||
| − | * '''Protein family:''' LysR family of transcription factors | + | * '''Protein family:''' [[LysR family]] of transcription factors |
* '''Paralogous protein(s):''' | * '''Paralogous protein(s):''' | ||
Revision as of 23:44, 17 November 2009
| Gene name | alsR |
| Synonyms | |
| Essential | no |
| Product | transcriptional activator(LysR family) |
| Function | regulation of acetoin synthesis (alsS-alsD) |
| Metabolic function and regulation of this protein in SubtiPathways: Central C-metabolism | |
| MW, pI | 34 kDa, 7.288 |
| Gene length, protein length | 906 bp, 302 aa |
| Immediate neighbours | alsS, ywrK |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU36020
Phenotypes of a mutant
no acetoin production
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: binds the promoter region of the alsS-alsD operon in the presence of acetate, activates transcription
- Protein family: LysR family of transcription factors
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: Q04778
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant: AMBs3 (spc), available in the Stülke lab
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Elisabeth Härtig, Braunschweig, Germany Homepage
Your additional remarks
References
M C Renna, N Najimudin, L R Winik, S A Zahler
Regulation of the Bacillus subtilis alsS, alsD, and alsR genes involved in post-exponential-phase production of acetoin.
J Bacteriol: 1993, 175(12);3863-75
[PubMed:7685336]
[WorldCat.org]
[DOI]
(P p)
