Difference between revisions of "FlgM"

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* '''Description:''' anti-SigD, regulation of flagellin, motility, and chemotaxis <br/><br/>
+
* '''Description:''' anti-[[SigD]], regulation of flagellin, motility, and chemotaxis <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || anti-SigD
+
|style="background:#ABCDEF;" align="center"| '''Product''' || anti-[[SigD]]
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || control of SigD activity
+
|style="background:#ABCDEF;" align="center"|'''Function''' || control of [[SigD]] activity
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 9 kDa, 9.918   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 9 kDa, 9.918   
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* '''Regulation:'''  
 
* '''Regulation:'''  
 +
** [[ScoC]]: transcription repression {{PubMed|19898538}}
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
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=References=
 
=References=
  
<pubmed>8955328,, </pubmed>
+
<pubmed>8955328,19898538 , </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 21:35, 10 November 2009

  • Description: anti-SigD, regulation of flagellin, motility, and chemotaxis

Gene name flgM
Synonyms
Essential no
Product anti-SigD
Function control of SigD activity
MW, pI 9 kDa, 9.918
Gene length, protein length 264 bp, 88 aa
Immediate neighbours yvyG, yvyF
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
FlgM context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU35430

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: flgM family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Prashant Kodgire, K Krishnamurthy Rao
A dual mode of regulation of flgM by ScoC in Bacillus subtilis.
Can J Microbiol: 2009, 55(8);983-9
[PubMed:19898538] [WorldCat.org] [DOI] (I p)

K Fredrick, J D Helmann
FlgM is a primary regulator of sigmaD activity, and its absence restores motility to a sinR mutant.
J Bacteriol: 1996, 178(23);7010-3
[PubMed:8955328] [WorldCat.org] [DOI] (P p)