Difference between revisions of "NrnA"
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| − | * '''Description:''' oligoribonuclease ( | + | * '''Description:''' oligoribonuclease (nano[[RNase]]), 3',5'-bisphosphate nucleotidase <br/><br/> |
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
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| − | |style="background:#ABCDEF;" align="center"| '''Product''' || oligoribonuclease ( | + | |style="background:#ABCDEF;" align="center"| '''Product''' || oligoribonuclease (nano[[RNAse]]), 3',5'-bisphosphate nucleotidase |
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || degradation of RNA oligonucleotides, | |style="background:#ABCDEF;" align="center"|'''Function''' || degradation of RNA oligonucleotides, | ||
Revision as of 11:07, 3 November 2009
- Description: oligoribonuclease (nanoRNase), 3',5'-bisphosphate nucleotidase
| Gene name | nrnA |
| Synonyms | ytqI |
| Essential | no |
| Product | oligoribonuclease (nanoRNAse), 3',5'-bisphosphate nucleotidase |
| Function | degradation of RNA oligonucleotides, |
| MW, pI | 34 kDa, 4.668 |
| Gene length, protein length | 939 bp, 313 aa |
| Immediate neighbours | ytrI, ytpI |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU29250
Phenotypes of a mutant
The mutant requires cysteine PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Adenosine 3',5'-bisphosphate + H2O = adenosine 5'-phosphate + phosphate (according to Swiss-Prot) oligoribonuclease (nanoRNAse), 3',5'-bisphosphate nucleotidase PubMed
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: Cytoplasm (Homogeneous) PubMed
Database entries
- Structure:
- UniProt: O34600
- KEGG entry: [3]
- E.C. number: 3.1.3.7
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Ming Fang, Wencke-Maria Zeisberg, Ciaran Condon, Vasily Ogryzko, Antoine Danchin, Undine Mechold
Degradation of nanoRNA is performed by multiple redundant RNases in Bacillus subtilis.
Nucleic Acids Res: 2009, 37(15);5114-25
[PubMed:19553197]
[WorldCat.org]
[DOI]
(I p)
Jiaqin Zhang, Indranil Biswas
3'-Phosphoadenosine-5'-phosphate phosphatase activity is required for superoxide stress tolerance in Streptococcus mutans.
J Bacteriol: 2009, 191(13);4330-40
[PubMed:19429620]
[WorldCat.org]
[DOI]
(I p)
Undine Mechold, Gang Fang, Saravuth Ngo, Vasily Ogryzko, Antoine Danchin
YtqI from Bacillus subtilis has both oligoribonuclease and pAp-phosphatase activity.
Nucleic Acids Res: 2007, 35(13);4552-61
[PubMed:17586819]
[WorldCat.org]
[DOI]
(I p)
Jean-Christophe Meile, Ling Juan Wu, S Dusko Ehrlich, Jeff Errington, Philippe Noirot
Systematic localisation of proteins fused to the green fluorescent protein in Bacillus subtilis: identification of new proteins at the DNA replication factory.
Proteomics: 2006, 6(7);2135-46
[PubMed:16479537]
[WorldCat.org]
[DOI]
(P p)
