Difference between revisions of "Smc"
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* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
− | * '''Interactions:''' [[ScpB]]-[[Smc]], [[ScpA]]-[[ | + | * '''Interactions:''' [[ScpB]]-[[Smc]] {{PubMed|12100548}}, [[ScpA]]-[[ScpB]] {{PubMed|12100548}} |
* '''Localization:''' | * '''Localization:''' |
Revision as of 11:38, 17 September 2009
- Description: chromosome condensation and segregation SMC protein
Gene name | smc |
Synonyms | ylqA |
Essential | yes PubMed |
Product | chromosome condensation and segregation SMC protein |
Function | structural maintenance of the chromosome |
MW, pI | 135 kDa, 5.266 |
Gene length, protein length | 3558 bp, 1186 aa |
Immediate neighbours | rnc, ftsY |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
|
Contents
The gene
Basic information
- Locus tag: BSU15940
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: SMC family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
Database entries
- Structure:
- UniProt: P51834
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Nora L Sullivan, Kathleen A Marquis, David Z Rudner
Recruitment of SMC by ParB-parS organizes the origin region and promotes efficient chromosome segregation.
Cell: 2009, 137(4);697-707
[PubMed:19450517]
[WorldCat.org]
[DOI]
(I p)
Stephan Gruber, Jeff Errington
Recruitment of condensin to replication origin regions by ParB/SpoOJ promotes chromosome segregation in B. subtilis.
Cell: 2009, 137(4);685-96
[PubMed:19450516]
[WorldCat.org]
[DOI]
(I p)
Robert A Britton, Elke Küster-Schöck, Thomas A Auchtung, Alan D Grossman
SOS induction in a subpopulation of structural maintenance of chromosome (Smc) mutant cells in Bacillus subtilis.
J Bacteriol: 2007, 189(12);4359-66
[PubMed:17416649]
[WorldCat.org]
[DOI]
(P p)
Janet C Lindow, Masayoshi Kuwano, Shigeki Moriya, Alan D Grossman
Subcellular localization of the Bacillus subtilis structural maintenance of chromosomes (SMC) protein.
Mol Microbiol: 2002, 46(4);997-1009
[PubMed:12421306]
[WorldCat.org]
[DOI]
(P p)
Jörg Soppa, Kazuo Kobayashi, Marie-Françoise Noirot-Gros, Dieter Oesterhelt, S Dusko Ehrlich, Etienne Dervyn, Naotake Ogasawara, Shigeki Moriya
Discovery of two novel families of proteins that are proposed to interact with prokaryotic SMC proteins, and characterization of the Bacillus subtilis family members ScpA and ScpB.
Mol Microbiol: 2002, 45(1);59-71
[PubMed:12100548]
[WorldCat.org]
[DOI]
(P p)
P L Graumann, R Losick
Coupling of asymmetric division to polar placement of replication origin regions in Bacillus subtilis.
J Bacteriol: 2001, 183(13);4052-60
[PubMed:11395470]
[WorldCat.org]
[DOI]
(P p)
P L Graumann, R Losick, A V Strunnikov
Subcellular localization of Bacillus subtilis SMC, a protein involved in chromosome condensation and segregation.
J Bacteriol: 1998, 180(21);5749-55
[PubMed:9791128]
[WorldCat.org]
[DOI]
(P p)