Difference between revisions of "YhdN"
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=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' | + | * '''Operon:''' ''[[ydhN]]-[[ydhO]]'' {{PubMed|10220166}} |
| − | * '''[[Sigma factor]]:''' [[SigB]] | + | * '''[[Sigma factor]]:''' [[SigB]] {{PubMed|10220166,15805528}} |
| − | * '''Regulation:''' induced by stress ([[SigB]]) | + | * '''Regulation:''' |
| − | ** | + | ** induced by stress ([[SigB]]) {{PubMed|10220166,15805528}} |
| + | ** induced upon malonyl-CoA limitation ([[FapR]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/12737802 PubMed] | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
** [[FapR]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/12737802 PubMed] | ** [[FapR]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/12737802 PubMed] | ||
| − | * '''Additional information:''' | + | * '''Additional information:''' |
=Biological materials = | =Biological materials = | ||
Revision as of 18:54, 5 September 2009
- Description: general stress protein, aldo/keto reductase
| Gene name | yhdN |
| Synonyms | |
| Essential | no |
| Product | aldo/keto reductase, specific for NADP |
| Function | unknown |
| MW, pI | 37 kDa, 4.77 |
| Gene length, protein length | 993 bp, 331 aa |
| Immediate neighbours | sigM, plsC |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU09530
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: aldo/keto reductase 2 family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure: 1PZ1
- UniProt: P80874
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Dirk Höper, Uwe Völker, Michael Hecker
Comprehensive characterization of the contribution of individual SigB-dependent general stress genes to stress resistance of Bacillus subtilis.
J Bacteriol: 2005, 187(8);2810-26
[PubMed:15805528]
[WorldCat.org]
[DOI]
(P p)
Andreas H Ehrensberger, David K Wilson
Structural and catalytic diversity in the two family 11 aldo-keto reductases.
J Mol Biol: 2004, 337(3);661-73
[PubMed:15019785]
[WorldCat.org]
[DOI]
(P p)
Gustavo E Schujman, Luciana Paoletti, Alan D Grossman, Diego de Mendoza
FapR, a bacterial transcription factor involved in global regulation of membrane lipid biosynthesis.
Dev Cell: 2003, 4(5);663-72
[PubMed:12737802]
[WorldCat.org]
[DOI]
(P p)
Anja Petersohn, Haike Antelmann, Ulf Gerth, Michael Hecker
Identification and transcriptional analysis of new members of the sigmaB regulon in Bacillus subtilis.
Microbiology (Reading): 1999, 145 ( Pt 4);869-880
[PubMed:10220166]
[WorldCat.org]
[DOI]
(P p)
