Difference between revisions of "BirA"
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| − | * '''Description:''' trigger enzyme: transcriptional repressor of the biotin operon / biotin-protein ligase <br/><br/> | + | * '''Description:''' [[trigger enzymes|trigger enzyme]]: transcriptional repressor of the biotin operon / biotin-protein ligase <br/><br/> |
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|style="background:#ABCDEF;" align="center"| '''Essential''' || yes [http://www.ncbi.nlm.nih.gov/pubmed/12682299 PubMed] | |style="background:#ABCDEF;" align="center"| '''Essential''' || yes [http://www.ncbi.nlm.nih.gov/pubmed/12682299 PubMed] | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Product''' || transcriptional repressor/ biotin-protein ligase | + | |style="background:#ABCDEF;" align="center"| '''Product''' || [[trigger enzymes|trigger enzyme]]transcriptional repressor/ biotin-protein ligase |
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || regulation of biotin synthesis, addition of biotin to proteins | |style="background:#ABCDEF;" align="center"|'''Function''' || regulation of biotin synthesis, addition of biotin to proteins | ||
Revision as of 05:43, 2 September 2009
- Description: trigger enzyme: transcriptional repressor of the biotin operon / biotin-protein ligase
| Gene name | birA |
| Synonyms | |
| Essential | yes PubMed |
| Product | trigger enzymetranscriptional repressor/ biotin-protein ligase |
| Function | regulation of biotin synthesis, addition of biotin to proteins |
| MW, pI | 36 kDa, 6.769 |
| Gene length, protein length | 975 bp, 325 aa |
| Immediate neighbours | panB, cca |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU22440
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP + biotin + apo-[acetyl-CoA:carbon-dioxide ligase (ADP-forming)] = AMP + diphosphate + [acetyl-CoA:carbon-dioxide ligase (ADP-forming)] (according to Swiss-Prot)
- Protein family: pyrroline-5-carboxylate reductase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P42975
- KEGG entry: [2]
- E.C. number: 6.3.4.15
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
