Difference between revisions of "GroES"
| Line 96: | Line 96: | ||
* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|1350776}} | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|1350776}} | ||
| − | * '''Regulation:''' induced by heat shock ([[HrcA]]) {{PubMed|1350777}} | + | * '''Regulation:''' induced by heat shock ([[HrcA]]) {{PubMed|1350777,8576042}} |
| − | * '''Regulatory mechanism:''' [[HrcA]]: transcription repression | + | * '''Regulatory mechanism:''' [[HrcA]]: transcription repression {{PubMed|8576042}} |
* '''Additional information:''' | * '''Additional information:''' | ||
| Line 124: | Line 124: | ||
=References= | =References= | ||
| − | <pubmed>1350777,1350776 , </pubmed> | + | <pubmed>1350777,1350776 ,8576042 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 19:04, 23 August 2009
- Description: chaperonin
| Gene name | groES |
| Synonyms | |
| Essential | yes PubMed |
| Product | chaperonin |
| Function | protein folding and re-folding |
| Metabolic function and regulation of this protein in SubtiPathways: Stress | |
| MW, pI | 10 kDa, 4.595 |
| Gene length, protein length | 282 bp, 94 aa |
| Immediate neighbours | ydiL, groEL |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU06020
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: groES chaperonin family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P28599
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Wolfgang Schumann, Bayreuth University, Germany Homepage
Your additional remarks
References
A Schulz, W Schumann
hrcA, the first gene of the Bacillus subtilis dnaK operon encodes a negative regulator of class I heat shock genes.
J Bacteriol: 1996, 178(4);1088-93
[PubMed:8576042]
[WorldCat.org]
[DOI]
(P p)
A Schmidt, M Schiesswohl, U Völker, M Hecker, W Schumann
Cloning, sequencing, mapping, and transcriptional analysis of the groESL operon from Bacillus subtilis.
J Bacteriol: 1992, 174(12);3993-9
[PubMed:1350777]
[WorldCat.org]
[DOI]
(P p)
M Li, S L Wong
Cloning and characterization of the groESL operon from Bacillus subtilis.
J Bacteriol: 1992, 174(12);3981-92
[PubMed:1350776]
[WorldCat.org]
[DOI]
(P p)
