Difference between revisions of "MurAA"
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Revision as of 13:11, 21 July 2009
- Description: UDP-N-acetylglucosamine 1-carboxyvinyltransferase
Gene name | murAA |
Synonyms | murA |
Essential | yes PubMed |
Product | UDP-N-acetylglucosamine 1-carboxyvinyltransferase |
Function | peptidoglycan precursor biosynthesis |
Metabolic function and regulation of this protein in SubtiPathways: Cell wall | |
MW, pI | 46 kDa, 5.45 |
Gene length, protein length | 1308 bp, 436 aa |
Immediate neighbours | spoIID, ywmB |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
|
Contents
The gene
Basic information
- Locus tag: BSU36760
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine = phosphate + UDP-N-acetyl-3-O-(1-carboxyvinyl)-D-glucosamine (according to Swiss-Prot)
- Protein family: MurA subfamily (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P70965
- KEGG entry: [3]
- E.C. number: 2.5.1.7
Additional information
- subject to Clp-dependent proteolysis upon glucose starvation PubMed
MurAA is subject to ClpC-ClpP-dependent degradation PubMed
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information: subject to Clp-dependent proteolysis upon glucose starvation PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References