Difference between revisions of "HemN"
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Revision as of 11:45, 21 July 2009
- Description: anaerobic coproporphyrinogen III oxidase
| Gene name | hemN |
| Synonyms | yqeR |
| Essential | no |
| Product | anaerobic coproporphyrinogen III oxidase |
| Function | heme biosynthesis |
| MW, pI | 41 kDa, 5.534 |
| Gene length, protein length | 1098 bp, 366 aa |
| Immediate neighbours | hrcA, lepA |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU25500
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Coproporphyrinogen-III + 2 S-adenosyl-L-methionine = protoporphyrinogen-IX + 2 CO2 + 2 L-methionine + 2 5'-deoxyadenosine (according to Swiss-Prot)
- Protein family: anaerobic coproporphyrinogen III oxidase family (according to Swiss-Prot)
- Paralogous protein(s): HemZ
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: P54304
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
G Homuth, A Rompf, W Schumann, D Jahn
Transcriptional control of Bacillus subtilis hemN and hemZ.
J Bacteriol: 1999, 181(19);5922-9
[PubMed:10498703]
[WorldCat.org]
[DOI]
(P p)
B Hippler, G Homuth, T Hoffmann, C Hungerer, W Schumann, D Jahn
Characterization of Bacillus subtilis hemN.
J Bacteriol: 1997, 179(22);7181-5
[PubMed:9371469]
[WorldCat.org]
[DOI]
(P p)
G Homuth, M Heinemann, U Zuber, W Schumann
The genes of lepA and hemN form a bicistronic operon in Bacillus subtilis.
Microbiology (Reading): 1996, 142 ( Pt 7);1641-9
[PubMed:8757728]
[WorldCat.org]
[DOI]
(P p)
