Difference between revisions of "Btr"
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− | * '''Description:''' transcription activator ( | + | * '''Description:''' transcription activator (AraC family DNA-binding domain fused to [[FeuA]]-like substrate-binding domain), regulation of the ''[[feuA]]-[[feuB]]-[[feuC]]-[[ybbA]]'' operon <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
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=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
− | * '''Catalyzed reaction/ biological activity:''' | + | * '''Catalyzed reaction/ biological activity:''' transcription activation of the ''[[feuA]]-[[feuB]]-[[feuC]]-[[ybbA]]'' operon in the presence of bacillibactin or enterobactin [http://www.ncbi.nlm.nih.gov/sites/entrez/17725565 PubMed] |
* '''Protein family:''' | * '''Protein family:''' | ||
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* '''Modification:''' | * '''Modification:''' | ||
− | * '''Cofactor(s):''' | + | * '''Cofactor(s):''' enterobactin, bacillibactin (co-activators) [http://www.ncbi.nlm.nih.gov/sites/entrez/17725565 PubMed] |
− | * '''Effectors of protein activity:''' | + | * '''Effectors of protein activity:''' enterobactin, bacillibactin (co-activators) [http://www.ncbi.nlm.nih.gov/sites/entrez/17725565 PubMed] |
* '''Interactions:''' | * '''Interactions:''' | ||
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* '''Regulation:''' | * '''Regulation:''' | ||
− | ** | + | ** expressed under conditions of iron starvation ([[Fur]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/12354229 PubMed] |
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' |
Revision as of 20:41, 27 June 2009
- Description: transcription activator (AraC family DNA-binding domain fused to FeuA-like substrate-binding domain), regulation of the feuA-feuB-feuC-ybbA operon
Gene name | btr |
Synonyms | ybbB, yzbC |
Essential | no |
Product | transcription activator (AraC family) |
Function | regulation of iron acquisition |
Metabolic function and regulation of this protein in SubtiPathways: Stress | |
MW, pI | 60 kDa, 6.433 |
Gene length, protein length | 1587 bp, 529 aa |
Immediate neighbours | feuA, ybbC |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
|
Contents
The gene
Basic information
- Locus tag: BSU01640
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: transcription activation of the feuA-feuB-feuC-ybbA operon in the presence of bacillibactin or enterobactin PubMed
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s): enterobactin, bacillibactin (co-activators) PubMed
- Effectors of protein activity: enterobactin, bacillibactin (co-activators) PubMed
- Interactions:
- Localization:
Database entries
- Structure:
- Swiss prot entry: P40408
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Additional information: the mRNA is very stable (half-life > 15 min) PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References