Difference between revisions of "FeuC"
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=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' | + | * '''Operon:''' ''[[feuA]]-[[feuB]]-[[feuC]]-[[ybbA]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/12354229 PubMed] |
| − | * '''[[Sigma factor]]:''' | + | * '''[[Sigma factor]]:''' [[SigA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/17725565 PubMed] |
* '''Regulation:''' | * '''Regulation:''' | ||
| − | ** repressed | + | ** repressed in the presence of iron ([[Fur]], [[CitB]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/12354229 PubMed] |
| + | ** induced in the presence of iron chelators bacillibactin or enterobactin ([[Btr]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/17725565 PubMed] | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
** [[Fur]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/12354229 PubMed] | ** [[Fur]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/12354229 PubMed] | ||
| + | ** [[CitB]]: binding to the iron responsive element in the absence of iron | ||
| + | ** [[Btr]]: transcription activation in the presence of the co-activators bacillibactin or enterobactin [http://www.ncbi.nlm.nih.gov/sites/entrez/17725565 PubMed] | ||
| − | * '''Additional information:''' | + | * '''Additional information:''' |
=Biological materials = | =Biological materials = | ||
Revision as of 20:10, 27 June 2009
- Description: ABC-transporter for the siderophores enterobactin and bacillibactin (integral membrane protein)
| Gene name | feuC |
| Synonyms | |
| Essential | no |
| Product | ABC-transporter for the siderophores enterobactin and bacillibactin (integral membrane protein) |
| Function | iron acquisition |
| Metabolic function and regulation of this protein in SubtiPathways: Stress | |
| MW, pI | 42 kDa, 10.435 |
| Gene length, protein length | 1182 bp, 394 aa |
| Immediate neighbours | ybbA, feuB |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU01610
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: FecCD subfamily (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- Structure:
- Swiss prot entry: P40411
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
