Difference between revisions of "PyrC"
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|style="background:#ABCDEF;" align="center"|'''Function''' || pyrimidine biosynthesis | |style="background:#ABCDEF;" align="center"|'''Function''' || pyrimidine biosynthesis | ||
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− | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/gene_regulation_nucleotides.html Nucleotides (regulation)]''' | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/pyrimidines_metabolism.html Pyrimidines], [http://subtiwiki.uni-goettingen.de/pathways/gene_regulation_nucleotides.html Nucleotides (regulation)]''' |
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 46 kDa, 5.427 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 46 kDa, 5.427 |
Revision as of 14:15, 18 June 2009
- Description: dihydroorotase
Gene name | pyrC |
Synonyms | |
Essential | no |
Product | dihydroorotase |
Function | pyrimidine biosynthesis |
Metabolic function and regulation of this protein in SubtiPathways: Pyrimidines, Nucleotides (regulation) | |
MW, pI | 46 kDa, 5.427 |
Gene length, protein length | 1284 bp, 428 aa |
Immediate neighbours | pyrB, pyrAA |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
|
Contents
The gene
Basic information
- Locus tag: BSU15500
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: (S)-dihydroorotate + H2O = N-carbamoyl-L-aspartate (according to Swiss-Prot)
- Protein family: Type 2 subfamily (according to Swiss-Prot)
- Paralogous protein(s): PucH
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- Swiss prot entry: P25995
- KEGG entry: [3]
- E.C. number: 3.5.2.3
Additional information
Expression and regulation
- Regulatory mechanism:
- PyrR: RNA switch, transcription termination/ antitermination (in the presence of uridine nucleotides: termination, in their absence: antitermination) PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References