Difference between revisions of "NupC"

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|style="background:#ABCDEF;" align="center"|'''Function''' || pyrimidine uptake  
 
|style="background:#ABCDEF;" align="center"|'''Function''' || pyrimidine uptake  
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/gene_regulation_nucleotides.html Nucleotides (regulation)]'''
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/nucleosides_catabolism.html Nucleoside catabolism], [http://subtiwiki.uni-goettingen.de/pathways/gene_regulation_nucleotides.html Nucleotides (regulation)]'''
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 42 kDa, 9.316   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 42 kDa, 9.316   

Revision as of 12:15, 18 June 2009

  • Description: pyrimidine nucleoside transport protein

Gene name nupC
Synonyms
Essential no
Product pyrimidine nucleoside transport protein
Function pyrimidine uptake
Metabolic function and regulation of this protein in SubtiPathways:
Nucleoside catabolism, Nucleotides (regulation)
MW, pI 42 kDa, 9.316
Gene length, protein length 1179 bp, 393 aa
Immediate neighbours pdp, dra
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
NupC context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU39410

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: SLC28A transporter family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cell membrane (according to Swiss-Prot), membrane associated PubMed

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation: repressed by glucose (CcpA)
  • Regulatory mechanism: CcpA: transcription repression
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References