FbaA

• Description: write here
  
  

Gene name	fbaA
Synonyms	fba, fba1, tsr
Essential	write here
Product	fructose-1,6-bisphosphate aldolase
Function	write here
MW, pI	xx,x kDa, y.yy
Gene length, protein length	aaa bp, bbb amino acids
Immediate neighbours	genA, genB
Gene sequence (+200bp)	Protein sequence
Genetic context File:GenE context.gif

The gene

Basic information

• Coordinates:

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate

• Protein family: class II fructose-bisphosphate aldolase family.

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:
  • 2 x Dihydroxyacetone phosphate binding domain (210–212), (231–234)

• Modification: Phosphorylated during sporulation

• Cofactor(s): 2 x zinc ion

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• Swiss prot entry: [3]

• KEGG entry: [4]

• E.C. number: [5]

Additional information

• • Binds 2 zinc ions per subunit. One is catalytic and the other provides a structural contribution

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

References

1. Trach K, Chapman JW & Piggot P (1988) Complete sequence and transcriptional analysis of the spo0F region of the Bacillus subtilis chromosome J Bacteriol. 170: 4194-4208. PubMed
2. Ludwig H, Homuth G & Schmalisch M (2001) Transcription of glycolytic genes and operons in Bacillus subtilis: evidence for the presence of multiple levels of control of the gapA operon Mol Microbiol. 41: 409-22. PubMed