Difference between revisions of "AraD"
| Line 95: | Line 95: | ||
* '''Regulation:''' repressed by glucose ([[CcpA]]) | * '''Regulation:''' repressed by glucose ([[CcpA]]) | ||
| + | ** repressed in the absence of arabinose ([[AraR]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/10417639 PubMed] | ||
* '''Regulatory mechanism:''' [[CcpA]]: transcription repression | * '''Regulatory mechanism:''' [[CcpA]]: transcription repression | ||
| + | ** [[AraR]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/10417639 PubMed] | ||
* '''Additional information:''' | * '''Additional information:''' | ||
Revision as of 11:44, 11 June 2009
- Description: L-ribulose-phosphate 4-epimerase
| Gene name | araD |
| Synonyms | |
| Essential | no |
| Product | L-ribulose-phosphate 4-epimerase |
| Function | arabinose utilization |
| Metabolic function and regulation of this protein in SubtiPathways: Sugar catabolism | |
| MW, pI | 25 kDa, 5.243 |
| Gene length, protein length | 687 bp, 229 aa |
| Immediate neighbours | araL, araB |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU28780
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: L-ribulose 5-phosphate = D-xylulose 5-phosphate (according to Swiss-Prot)
- Protein family: AraD/fucA subfamily (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- Swiss prot entry: P94525
- KEGG entry: [3]
- E.C. number: 5.1.3.4
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
- Inácio JM, Costa C, de Sá-Nogueira I. (2003) Distinct molecular mechanisms involved in carbon catabolite repression of the arabinose regulon in Bacillus subtilis. Microbiology. Sep;149(Pt 9): 2345-55. PubMed
- Sa-Nogueira I.M.G., Nogueira T.V., Soares S., de Lencastre H. (1997) The Bacillus subtilis L-arabinose (ara) operon: nucleotide sequence, genetic organization and expression. Microbiology. Mar;143(Pt 3): 957-69. PubMed
- Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed
