Difference between revisions of "GyrB"
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=== Basic information === | === Basic information === | ||
| − | * '''Locus tag:''' | + | * '''Locus tag:''' BSU00060 |
===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
| Line 82: | Line 82: | ||
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P05652 P05652] | * '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P05652 P05652] | ||
| − | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+ | + | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU00060] |
* '''E.C. number:''' | * '''E.C. number:''' | ||
Revision as of 13:51, 3 June 2009
- Description: DNA-Gyrase (subunit B)
| Gene name | gyrB |
| Synonyms | novA |
| Essential | yes PubMed |
| Product | DNA-Gyrase (subunit B) |
| Function | DNA supercoiling, initation of replication cycle and DNA elongation |
| MW, pI | 71 kDa, 5.378 |
| Gene length, protein length | 1914 bp, 638 aa |
| Immediate neighbours | yaaB, gyrA |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU00060
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP-dependent breakage, passage and rejoining of double-stranded DNA (according to Swiss-Prot)
- Protein family: type II topoisomerase family (according to Swiss-Prot)
- Paralogous protein(s): ParE
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: nucleoid-associated in actively growing cells PubMed
Database entries
- Structure:
- Swiss prot entry: P05652
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information: GyrB is subject to Clp-dependent proteolysis upon glucose starvation PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Dagmar Klostermeier, Biozentrum Basel, Switzerland homepage
Your additional remarks
References
