Difference between revisions of "RacE"
| Line 37: | Line 37: | ||
=== Basic information === | === Basic information === | ||
| − | * '''Locus tag:''' | + | * '''Locus tag:''' BSU28390 |
===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
| Line 84: | Line 84: | ||
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P94556 P94556] | * '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P94556 P94556] | ||
| − | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+ | + | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU28390] |
* '''E.C. number:''' [http://www.expasy.org/enzyme/5.1.1.3 5.1.1.3] | * '''E.C. number:''' [http://www.expasy.org/enzyme/5.1.1.3 5.1.1.3] | ||
Revision as of 12:01, 3 June 2009
- Description: glutamate racemase
| Gene name | racE |
| Synonyms | glr |
| Essential | yes PubMed |
| Product | glutamate racemase |
| Function | peptidoglycan precursor biosynthesis |
| MW, pI | 29 kDa, 4.858 |
| Gene length, protein length | 816 bp, 272 aa |
| Immediate neighbours | gerM, ysmB |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU28390
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: L-glutamate = D-glutamate (according to Swiss-Prot)
- Protein family: aspartate/glutamate racemases family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure: 1ZUW (with D-glutamate)
- Swiss prot entry: P94556
- KEGG entry: [2]
- E.C. number: 5.1.1.3
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
M Ashley Spies, Joseph G Reese, Dylan Dodd, Katherine L Pankow, Steven R Blanke, Jerome Baudry
Determinants of catalytic power and ligand binding in glutamate racemase.
J Am Chem Soc: 2009, 131(14);5274-84
[PubMed:19309142]
[WorldCat.org]
[DOI]
(I p)
Eduard Puig, Edgar Mixcoha, Mireia Garcia-Viloca, Angels González-Lafont, José M Lluch
How the substrate D-glutamate drives the catalytic action of Bacillus subtilis glutamate racemase.
J Am Chem Soc: 2009, 131(10);3509-21
[PubMed:19227983]
[WorldCat.org]
[DOI]
(I p)
- Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed
