Difference between revisions of "MurB"

From SubtiWiki
Jump to: navigation, search
Line 35: Line 35:
 
=== Basic information ===
 
=== Basic information ===
  
* '''Locus tag:'''
+
* '''Locus tag:''' BSU15230
  
 
===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
Line 82: Line 82:
 
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P18579 P18579]
 
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P18579 P18579]
  
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU15230 BSU15230]
+
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU15230]
  
 
* '''E.C. number:''' [http://www.expasy.org/enzyme/1.1.1.158 1.1.1.158]
 
* '''E.C. number:''' [http://www.expasy.org/enzyme/1.1.1.158 1.1.1.158]

Revision as of 11:50, 3 June 2009

  • Description: UDP-N-acetylenolpyruvoylglucosamine reductase

Gene name murB
Synonyms ylxC
Essential yes PubMed
Product UDP-N-acetylenolpyruvoylglucosamine reductase
Function peptidoglycan precursor biosynthesis
MW, pI 32 kDa, 6.087
Gene length, protein length 909 bp, 303 aa
Immediate neighbours murG, divIB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
MurB context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU15230

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: UDP-N-acetylmuramate + NADP+ = UDP-N-acetyl-3-O-(1-carboxyvinyl)-D-glucosamine + NADPH (according to Swiss-Prot)
  • Protein family: FAD-binding PCMH-type domain (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cytoplasm (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Adriano Henriques, Lisbon, Portugal homepage

Your additional remarks

References

  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed