Difference between revisions of "TrxB"

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=== Basic information/ Evolution ===
 
=== Basic information/ Evolution ===
  
* '''Catalyzed reaction/ biological activity:'''  
+
* '''Catalyzed reaction/ biological activity:''' Thioredoxin + NADP<sup>+</sup> = thioredoxin disulfide + NADPH (according to Swiss-Prot)
  
 
* '''Protein family:''' class-II pyridine nucleotide-disulfide oxidoreductase family (according to Swiss-Prot)
 
* '''Protein family:''' class-II pyridine nucleotide-disulfide oxidoreductase family (according to Swiss-Prot)

Revision as of 14:41, 24 May 2009

  • Description: thioredoxin reductase (NADPH)

Gene name trxB
Synonyms yvcH
Essential yes PubMed
Product thioredoxin reductase (NADPH)
Function keeps thioredoxin in the reduced state
MW, pI 34 kDa, 4.99
Gene length, protein length 948 bp, 316 aa
Immediate neighbours yvcI, cwlO
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
TrxB context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Thioredoxin + NADP+ = thioredoxin disulfide + NADPH (according to Swiss-Prot)
  • Protein family: class-II pyridine nucleotide-disulfide oxidoreductase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cytoplasm (according to Swiss-Prot)

Database entries

  • Structure:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed