Difference between revisions of "MetC"
| Line 54: | Line 54: | ||
=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
| − | * '''Catalyzed reaction/ biological activity:''' | + | * '''Catalyzed reaction/ biological activity:''' L-cystathionine + H<sub>2</sub>O = L-homocysteine + NH<sub>3</sub> + pyruvate (according to Swiss-Prot) |
* '''Protein family:''' trans-sulfuration enzymes family (according to Swiss-Prot) | * '''Protein family:''' trans-sulfuration enzymes family (according to Swiss-Prot) | ||
Revision as of 17:00, 23 May 2009
- Description: cystathionine b-lyase
| Gene name | metC |
| Synonyms | yjcJ |
| Essential | no |
| Product | cystathionine b-lyase |
| Function | biosynthesis of methionine |
| MW, pI | 42 kDa, 5.757 |
| Gene length, protein length | 1170 bp, 390 aa |
| Immediate neighbours | metI, yjcK |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Coordinates:
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: L-cystathionine + H2O = L-homocysteine + NH3 + pyruvate (according to Swiss-Prot)
- Protein family: trans-sulfuration enzymes family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure:
- Swiss prot entry: O31632
- KEGG entry: BSU11880
- E.C. number: 4.4.1.8
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation: repressed by casamino acids PubMed
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
