Difference between revisions of "SdhC"
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* '''[[Sigma factor]]:''' [[SigA]] | * '''[[Sigma factor]]:''' [[SigA]] | ||
| − | * '''Regulation:''' | + | * '''Regulation:''' SdhC is less expressed under conditions of extreme iron starvation |
* '''Regulatory mechanism:''' [[FsrA]]: translational repression [http://www.ncbi.nlm.nih.gov/pubmed/18697947 PubMed] | * '''Regulatory mechanism:''' [[FsrA]]: translational repression [http://www.ncbi.nlm.nih.gov/pubmed/18697947 PubMed] | ||
| − | |||
* '''Additional information:''' | * '''Additional information:''' | ||
Revision as of 11:10, 21 May 2009
- Description: succinate dehydrogenase(cytochrome b558 subunit)
| Gene name | sdhC |
| Synonyms | |
| Essential | no |
| Product | succinate dehydrogenase (cytochrome b558 subunit) |
| Function | TCA cycle |
| MW, pI | 22 kDa, 9.831 |
| Gene length, protein length | 606 bp, 202 aa |
| Immediate neighbours | yslB, sdhA |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Coordinates:
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cell membrane (according to Swiss-Prot), membrane protein PubMed
Database entries
- Structure: 1NEK (E. coli)
- Swiss prot entry: P08064
- KEGG entry: BSU28450
- E.C. number: 1.3.99.1
Additional information
Expression and regulation
- Regulation: SdhC is less expressed under conditions of extreme iron starvation
- Additional information:
Biological materials
- Mutant: GP743 (sdhCA, cat), available in Stülke lab
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
- Hahne et al. (2008) From complementarity to comprehensiveness - targeting the membrane proteome of growing Bacillus subtilis by divergent approaches. Proteomics 8: 4123-4136 PubMed# Hahne et al. (2008) From complementarity to comprehensiveness - targeting the membrane proteome of growing Bacillus subtilis by divergent approaches. Proteomics 8: 4123-4136 PubMed
- Gaballa A, Antelmann H, Aguilar C, Khakh SK, Song KB, Smaldone GT, Helmann JD (2008) The Bacillus subtilis iron-sparing response is mediated by a Fur-regulated small RNA and three small, basic proteins. PNAS 105: 11927-11932. PubMed
- Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed
